Medical Scientist how-to
How to Design a Phase I Trial
Phase I tests safety.
Quick answer
Phase I tests safety. In short: define; pick; plan, then complete the remaining steps below.
Step by step
Define objectives.
Pick starting dose.
Plan dose escalation.
Define safety endpoints.
Get IRB approval.
Enroll carefully.
Safety reminders for medical scientists
- Follow IRB rules
- Follow biosafety
- Protect patient data
- Report adverse events
Key terms
Hypothesis · Peer review · Grant · Protocol · Replication · Clinical trial: see the full medical scientist glossary.