Chemist how-to

How to Develop an Analytical Method

Good methods are accurate and repeatable.

Updated By the Career Education Institute Curriculum Team
Quick answer

Good methods are accurate and repeatable. In short: define; choose; optimize, then complete the remaining steps below.

Step by step

  1. Define the goal.

  2. Choose a technique.

  3. Optimize conditions.

  4. Test specificity.

  5. Validate accuracy and precision.

  6. Write the SOP.

Safety reminders for chemists

  • Read SDS and assess hazards
  • Use fume hoods and PPE
  • Store chemicals properly
  • Dispose of waste correctly

HPLC · GC-MS · NMR · Synthesis · Method validation · Specificity: see the full chemist glossary.

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