Chemist how-to
How to Develop an Analytical Method
Good methods are accurate and repeatable.
Quick answer
Good methods are accurate and repeatable. In short: define; choose; optimize, then complete the remaining steps below.
Step by step
Define the goal.
Choose a technique.
Optimize conditions.
Test specificity.
Validate accuracy and precision.
Write the SOP.
Safety reminders for chemists
- Read SDS and assess hazards
- Use fume hoods and PPE
- Store chemicals properly
- Dispose of waste correctly
Key terms
HPLC · GC-MS · NMR · Synthesis · Method validation · Specificity: see the full chemist glossary.
